Diabetic Nephropathy- Symptoms and Diagnosis
A kidney disease caused due to long term diabetes, as 15 years or more, is also known as Kimmelstiel-Wilson syndrome and intercapillary glomerulonephritis. Long term diabetes’ kidney disease regarded as the main cause of dialysis, characterized by nephrotic syndrome.
Generally kidney defects, diseases, and infections are caused in diabetics due to persistent high levels of blood sugar that pass into urine in order to be secreted out. It can be found in both Type 1 and Type 2 diabetics. In Type1 patients, insulin production is diminished, and in Type2 patients, once called non-insulin diabetes mellitus, or adult onset diabetes results as insulin deficiency or insulin resistance.
Uncontrolled sugar levels however are fatal for both types of diabetics. Cardiovascular diseases, impairment of several body organs, muscle weakness, nephropathy, blindness, memory loss, artery diseases, and most commonly heightened healing defects are some of the defects and ailments caused due to excessive hypoglycemia or hyperglycemia.
Higher levels of Insulin may increase breast cancer risk
A new study suggests that women, who have higher levels of insulin in blood, are more prone to breast cancer that the women with its lower levels.
Higher levels of insulin are already linked with obesity and according to a team from Albert Einstein College, New York City it may also serve as a link between breast cancer and obesity.
In their study, the researchers made a comparison of insulin levels of 835 women who had breast cancer with 816 women who hadn’t developed the disease. All the participants of the study were taking part in the study of Women’s Health Initiative. The researchers found that women with higher levels of insulin had a considerable higher risk for breast cancer than the women with lower levels of insulin.
Cancer drug may be helpful to treat Type 1 diabetes
Gleevac, which is considered a wonder drug to treat leukemia and other cancers, may also prove helpful to reverse type1 diabetes, researchers from University of California San Francisco find.
While noticing effects on mice, the researchers also found that Gleevec and another similar cancer drug Sutent helped to avoid the development of type1 diabetes. Type1 diabetes occurs because of the body’s inability to produce insulin and more often it is diagnosed in children and young adults.
Jeffrey Bluestone, who led the study, says: “ Gleevec seems to affect related kinases even platelet-derived growth factor that are possibly involved in different cell types grave to the progression and development of autoimmune disease like type1 diabetes”.
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